Investigating whether a new method for measuring the ‘visual field’ can better detect glaucoma in short-sighted individuals
Description of the project:
This study will investigate different methods of measuring the ‘visual field’ to allow the research and development of new tests that may be better at detecting glaucoma and differentiating the disease from changes that can occur in healthy eyes, such as those related to the eye becoming short-sighted (myopic).
Who is eligible to take part?
Individuals aged 35-90 years with open-angle or normal-tension glaucoma (excluding glaucoma related to eye trauma) in one or both eyes.
Where and how will the research take place?
If you agree to take part, you will be invited to undergo some tests of vision lasting approximately 2 hours 30 minutes. This can be completed at the Centre for Optometry and Vision Science at the Ulster University Coleraine Campus, or the Northern Ireland Clinical Research Network Vision Suite within the Belfast Health & Social Care Trust (Royal Victoria Hospital site) depending on your preference.
These tests may be undertaken in one visit or split into two depending on preference. For the experimental tests, we will ask you to view different spots of light presented on a screen and measure the number and function of your eye’s retinal nerve cells. Before doing any experiments, we will perform some screening tests to ensure that you are eligible to participate. These screening tests will likely be familiar to you from a previous visit to your optometrist or the hospital eye service.
If you would like to take part or hear more about the research, please get in contact with Ms Caitlín Campbell via email at campbell-c118@ulster.ac.uk.
Clinical trial on a new treatment for glaucoma: oral cannabinoids
Description of the project:
Current treatments for glaucoma include eye drops, laser treatment and surgery. Drops can be difficult to use or not well tolerated. The need for better treatments is a top research priority identified by patients. This study will evaluate a new treatment, a synthetic cannabinoid, given in tablets, in patients with glaucoma. It is well known cannabinoids lower the eye pressure. The medication to be used in this study is currently been evaluated in other health areas and appears to be well tolerated and safe. The trial will recruit 10 patients with high eye pressure or mild glaucoma at the Belfast NHS trust. If treatment proves effective and well tolerated it will lead to a larger, definitive trial and, eventually, it could significantly improve outcomes of patients with glaucoma. The trial is sponsored by the Belfast Trust and supported by Glaucoma UK.
Who is eligible to take part?
People living in Northern Ireland with high eye pressure (high intraocular pressure) and people with mild glaucoma
Where and how will the research take place?
At the Belfast City Hospital, University Floor, at the NICRF. It will involve four or five visits to the research facility, lasting about one hour each. Participants will receive a £30 voucher for each visit.
If you would like to take part or hear more about the research, please get in contact with Professor Augusto Azuara-Blanco via email at a.azuara-blanco@qub.ac.uk
Help shape a new quality of life measure for people with sight loss
Description of the project:
Researchers are developing a new quality of life questionnaire for people living with eye disease and sight loss. Existing questionnaires have limitations and may not fully reflect the experiences of people living with sight loss in the UK today. This new questionnaire will help researchers and healthcare professionals understand how eye conditions and treatments affect everyday life.
Who is eligible to take part?
Those who are regularly attending the hospital eye department or those who have any eye condition that impacts their sight (that can’t be corrected with glasses).
Where and how will the research take place?
You will be invited to take part in an initial online discussion to share your experiences and views on living with eye disease or sight loss and to discuss which aspects of quality of life are most important to you.
If you are interested in taking part, fill in the short form on the Health and Care Research Wales website.